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Poxvirus

Publications related to poxviruses by MARCE participants.

  • Aldaz-Carroll L, Whitbeck JC, de Leon MP, Lou H, Pannell LK, Lebowitz J, Fogg C, White CL, Moss B, Cohen GH, and Eisenberg RJ: Physical and immunological characterization of a recombinant secreted form of the membrane protein encoded by the vaccinia virus L1R gene. Virology 2005, 341: 59-71 PubMed link

  • Aldaz-Carroll L, Whitbeck JC, Ponce dL, Lou H, Hirao L, Isaacs SN, Moss B, Eisenberg RJ, and Cohen GH: Epitope-mapping studies define two major neutralization sites on the vaccinia virus extracellular enveloped virus glycoprotein B5R. J Virol 2005, 79: 6260-6271 PubMed link

  • Aldaz-Carroll L, Xiao Y, Whitbeck JC, de Leon MP, Lou H, Kim M, Yu J, Reinherz EL, Isaacs SN, Eisenberg RJ, and Cohen GH: Major neutralizing sites on vaccinia virus glycoprotein B5 are exposed differently on variola virus ortholog B6. J Virol 2007, 81: 8131-8139 PubMed link

  • Bell E, Shamim M, Whitbeck JC, Sfyroera G, Lambris JD, and Isaacs SN: Antibodies against the extracellular enveloped virus B5R protein are mainly responsible for the EEV neutralizing capacity of vaccinia immune globulin. Virology 2004, 325: 425-431 PubMed link

  • Chen Z, Earl P, Americo J, Damon I, Smith SK, Yu F, Sebrell A, Emerson S, Cohen G, Eisenberg RJ, Gorshkova I, Schuck P, Satterfield W, Moss B, and Purcell R: Characterization of chimpanzee/human monoclonal antibodies to vaccinia virus A33 glycoprotein and its variola virus homolog in vitro and in a vaccinia virus mouse protection model. J Virol 2007, 81: 8989-8995 PubMed link

  • Chen Z, Earl P, Americo J, Damon I, Smith SK, Zhou YH, Yu F, Sebrell A, Emerson S, Cohen G, Eisenberg RJ, Svitel J, Schuck P, Satterfield W, Moss B, and Purcell R: Chimpanzee/human mAbs to vaccinia virus B5 protein neutralize vaccinia and smallpox viruses and protect mice against vaccinia virus. Proc Natl Acad Sci U S A 2006, 103: 1882-1887 PubMed link

  • Culyba MJ, Harrison JE, Hwang Y, and Bushman FD: DNA cleavage by the A22R resolvase of vaccinia virus. Virology 2006, 352: 466-476 PubMed link

  • Earl PL, Americo JL, Wyatt LS, Eller LA, Whitbeck JC, Cohen GH, Eisenberg RJ, Hartmann CJ, Jackson DL, Kulesh DA, Martinez MJ, Miller DM, Mucker EM, Shamblin JD, Zwiers SH, Huggins JW, Jahrling PB, and Moss B: Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox. Nature 2004, 428: 182-185 PubMed link

  • Fogg C, Lustig S, Whitbeck JC, Eisenberg RJ, Cohen GH, and Moss B: Protective immunity to vaccinia virus induced by vaccination with multiple recombinant outer membrane proteins of intracellular and extracellular virions. J Virol 2004, 78: 10230-10237 PubMed link

  • Fogg CN, Americo JL, Lustig S, Huggins JW, Smith SK, Damon I, Resch W, Earl PL, Klinman DM, and Moss B: Adjuvant-enhanced antibody responses to recombinant proteins correlates with protection of mice and monkeys to orthopoxvirus challenges. Vaccine 2007, 25: 2787-2799 PubMed link

  • Golovkin M, Spitsin S, Andrianov V, Smirnov Y, Xiao Y, Pogrebnyak N, Markley K, Brodzik R, Gleba Y, Isaacs SN, and Koprowski H: Smallpox subunit vaccine produced in planta confers protection in mice. Proc Natl Acad Sci U S A 2007, 104: 6864-6869 PubMed link

  • Hwang Y, Minkah N, Perry K, Van Duyne GD, and Bushman FD: Regulation of catalysis by the smallpox virus topoisomerase. J Biol Chem 2006, 281: 38052-38060 PubMed link

  • Izmailyan RA, Huang CY, Mohammad S, Isaacs SN, and Chang W: The envelope G3L protein is essential for entry of vaccinia virus into host cells. J Virol 2006, 80: 8402-8410 PubMed link

  • Jing L, Chong TM, Byrd B, McClurkan CL, Huang J, Story BT, Dunkley KM, Aldaz-Carroll L, Eisenberg RJ, Cohen GH, Kwok WW, Sette A, and Koelle DM: Dominance and diversity in the primary human CD4 T cell response to replication-competent vaccinia virus. J Immunol 2007, 178: 6374-6386 PubMed link

  • Lawrence SJ, Lottenbach KR, Newman FK, Buller RM, Bellone CJ, Chen JJ, Cohen GH, Eisenberg RJ, Belshe RB, Stanley SL, Jr., and Frey SE: Antibody responses to vaccinia membrane proteins after smallpox vaccination. J Infect Dis 2007, 196: 220-229 PubMed link

  • Lustig S, Fogg C, Whitbeck JC, Eisenberg RJ, Cohen GH, and Moss B: Combinations of polyclonal or monoclonal antibodies to proteins of the outer membranes of the two infectious forms of vaccinia virus protect mice against a lethal respiratory challenge. J Virol 2005, 79: 13454-13462 PubMed link

  • Lustig S, Fogg C, Whitbeck JC, and Moss B: Synergistic neutralizing activities of antibodies to outer membrane proteins of the two infectious forms of vaccinia virus in the presence of complement. Virology 2004, 328: 30-35 PubMed link

  • Minkah N, Hwang Y, Perry K, Van Duyne GD, Hendrickson R, Lefkowitz EJ, Hannenhalli S, and Bushman FD: Variola virus topoisomerase: DNA cleavage specificity and distribution of sites in Poxvirus genomes. Virology 2007, 365: 60-69 PubMed link

  • Perry K, Hwang Y, Bushman FD, and Van Duyne GD: Structural basis for specificity in the poxvirus topoisomerase. Mol Cell 2006, 23: 343-354 PubMed link

  • Viner KM and Isaacs SN: Activity of vaccinia virus-neutralizing antibody in the sera of smallpox vaccinees. Microbes Infect 2005, 7: 579-583 PubMed link

  • Wang GP and Bushman FD: A statistical method for comparing viral growth curves. J Virol Methods 2006, 135: 118-123 PubMed link

  • Weaver JR, Shamim M, Alexander E, Davies DH, Felgner PL, and Isaacs SN: The identification and characterization of a monoclonal antibody to the vaccinia virus E3 protein. Virus Res 2007, 130: 269-274 PubMed link

  • Xiao Y, Aldaz-Carroll L, Ortiz AM, Whitbeck JC, Alexander E, Lou H, Davis HL, Braciale TJ, Eisenberg RJ, Cohen GH, and Isaacs SN: A protein-based smallpox vaccine protects mice from vaccinia and ectromelia virus challenges when given as a prime and single boost. Vaccine 2007, 25: 1214-1224 PubMed link