Program V. Diagnostics: Development, Support and Discovery
Shepherds: Richard Rothman, Chris Geddes
Universal Nucleic Acid Amplification Tests (NAAT) - Diagnostics Hub 1
Universal Nucleic Acid Amplification Test (NAAT) platforms rely on the discovery that conserved and variable sequences contained in all human pathogens can be exploited for development of robust rapid diagnostic methods. We will grow two already advanced broad based diagnostic platforms which will both support Program Projects in the Center, and establish utility for dual use, i.e. biodefense/emerging infections and commonly encountered clinical infections, increasing likelihood of commercialization.
Multiplexed Ultra Fast and Sensitive Bioagent Assays - Diagnostics Hub 2
Fast, sensitive and agent specific tests are the fundamental underlying technologies behind the development of Bioagent diagnostic devices. Technologies which are widely used today such as RT-PCR, are either agent specific but not fast enough, or require sample collection in the field for analytical evaluation by a suite of approaches in a laboratory both some time and distance away. Even when in the laboratory, the collected samples can still take many hrs to analyze individually.
Developmental Diagnostic Projects
In addition to the projects described above, additional Developmental Diagnostic Projects are currently underway, and are described in the linked page below.